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It is responsible for the transfer of phosphate from ATP to Ser or Thr residues in substrates.The autoinhibitory domain features a pseudosubstrate site, which binds to the catalytic domain and blocks its ability to phosphorylate proteins.
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Our relationship was beautiful, until after we graduated and got married and have 2 lovely kids.
We both have jobs and took out a mortgage, however.
Ca MKII accounts for 1–2% of all proteins in the brain, and has 28 different isoforms.